Experience-dependent changes in cerebral activation during human REM sleep

被引：449

作者：

Maquet, P

Laureys, S

Peigneux, P

Fuchs, S

Petiau, C

Phillips, C

Aerts, J

Del Fiore, G

Degueldre, C

Meulemans, T

Luxen, A

Franck, G

Van der Linden, M

Smith, C

Cleeremans, A

机构：

[1] Univ Liege, Cyclotron Res Ctr, B-4000 Liege, Belgium

[2] Univ Liege, Dept Neuropsychol, B-4000 Liege, Belgium

[3] Trent Univ, Dept Psychol, Peterborough, ON K9J 7B8, Canada

[4] Free Univ Brussels, Cognit Sci Res Unit, B-1050 Brussels, Belgium

来源：

NATURE NEUROSCIENCE | 2000年 / 3卷 / 08期

关键词：

D O I：

10.1038/77744

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The function of rapid-eye-movement (REM) sleep is still unknown. One prevailing hypothesis suggests that REM sleep is important in processing memory traces. Here, using positron emission tomography (PET) and regional cerebral blood flow measurements, we show that waking experience influences regional brain activity during subsequent sleep. Several brain areas activated during the execution of a serial reaction time task during wakefulness were significantly more active during REM sleep in subjects previously trained on the task than in non-trained subjects. These results support the hypothesis that memory traces are processed during REM sleep in humans.

引用

页码：831 / 836

页数：6

共 48 条

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