Asymmetric synthesis of 2-deoxy-2-fluoro-gamma-aldonolactones and their conversion to 2-deoxy-2-fluoropentoses

被引：38

作者：

Davis, FA

Qi, HY

机构：

[1] Department of Chemistry, Temple University, Philadelphia

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 25期

关键词：

D O I：

10.1016/0040-4039(96)00825-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Fluoro-2-deoxy-gamma-xylonic and -lyxonic lactones, 7a and 7b, were prepared via the diastereoselective fluorination of the alpha,beta-unsaturated chiral imide 5 followed by dihydroxylation. Lactones 7a and 7b were converted to 2-deoxy-2-fluoro-xylo-D-pyranose (1) and 2-deoxy-2-fluoro-lyxo-L-pyranose (2) by reduction and deprotection. Copyright (C) 1996 Elsevier Science Ltd.

引用

页码：4345 / 4348

页数：4

共 30 条

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