Recurrence of ANCA-positive glomerulonephritis immediately after renal transplantation

被引：18

作者：

Lobbedez, T ^{[1
]}

Comoz, F ^{[1
]}

Renaudineau, E ^{[1
]}

Pujo, M ^{[1
]}

Ryckelynck, JP ^{[1
]}

de Ligny, BH ^{[1
]}

机构：

[1] Caen Univ Hosp, Nephrol & Pathol Dept, Caen, France

来源：

AMERICAN JOURNAL OF KIDNEY DISEASES | 2003年 / 42卷 / 04期

关键词：

kidney transplantation; crescentic necrotizing glomerulonephritis; antineutrophil cytoplasmic autoantibody (ANCA); plasma exchange;

D O I：

10.1053/S0272-6386(03)00917-X

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Recurrence of crescentic necrotizing glomerulonephritis after renal transplantation is rare. Successful renal transplantation in patients with antineutrophil cytoplasmic autoantibody (ANCA) glomerulonephritis has been reported. The presence of ANCA at transplantation does not appear to increase the rate of relapse after kidney allografting. Therapy with cyclophosphamide and corticoids usually is effective. We report a case of recurrent perinuclear ANCA crescentic necrotizing glomerulonephritis immediately after renal transplantation that was treated successfully by cyclophosphamide, plasma exchange, and intravenous polyvalent immunoglobulin.

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页数：5

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