Progress toward a rationally designed molecular motor

被引：223

作者：

Kelly, TR ^{[1
]}

机构：

[1] Boston Coll, Dept Chem, Eugene F Merkert Chem Ctr, Chestnut Hill, MA 02467 USA

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 2001年 / 34卷 / 06期

关键词：

D O I：

10.1021/ar000167x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A retrospective overview of the work in the author's laboratory leading to a prototype (43a) of a chemically powered molecular motor is provided. Beginning with a molecular brake (23) and then proceeding through a molecular "ratchet" (31), the development of a rationally designed molecular motor is described. The thermodynamic underpinnings of the concept are outlined, the synthetic routes to 23, 31, and 43a, are summarized, and the data documenting the function of 23, 31, and 43a are presented.

引用

页码：514 / 522

页数：9

共 20 条

[1]

[Anonymous], CHEMTRACTS ORG CHEM

[2]

Davis AP, 1998, ANGEW CHEM INT EDIT, V37, P909, DOI 10.1002/(SICI)1521-3773(19980420)37:7<909::AID-ANIE909>3.0.CO

[3]

2-X

[4] A rationally designed prototype of a molecular motor [J].

Kelly, TR ;

Silva, RA ;

De Silva, H ;

Jasmin, S ;

Zhao, YJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (29) :6935-6949

[5] Unidirectional rotary motion in a molecular system [J].

Kelly, TR ;

De Silva, H ;

Silva, RA .

NATURE, 1999, 401 (6749) :150-152

[6] BISUBSTRATE REACTION TEMPLATES - EXAMINATION OF THE CONSEQUENCES OF IDENTICAL VERSUS DIFFERENT BINDING-SITES [J].

KELLY, TR ;

BRIDGER, GJ ;

ZHAO, C .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (22) :8024-8034

[7] In search of molecular ratchets [J].

Kelly, TR ;

Tellitu, I ;

Sestelo, JP .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1997, 36 (17) :1866-1868

[8] A RECEPTOR FOR THE ORIENTED BINDING OF URIC-ACID TYPE MOLECULES [J].

KELLY, TR ;

MAGUIRE, MP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (21) :6549-6551

[9] A BISUBSTRATE REACTION TEMPLATE [J].

KELLY, TR ;

ZHAO, C ;

BRIDGER, GJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (10) :3744-3745

[10] A MOLECULAR BRAKE [J].

KELLY, TR ;

BOWYER, MC ;

BHASKAR, KV ;

BEBBINGTON, D ;

GARCIA, A ;

LANG, FR ;

KIM, MH ;

JETTE, MP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (08) :3657-3658

← 1 2 →