Improvement in health care utilization and pulmonary function with fluticasone propionate in patients with steroid-dependent asthma at a National Asthma Referral Center

被引:4
作者
Wenzel, SE [1 ]
Morgan, K [1 ]
Griffin, R [1 ]
Stanford, R [1 ]
Edwards, L [1 ]
Wamboldt, FS [1 ]
Rogenes, P [1 ]
机构
[1] Natl Jewish Med & Res Ctr, Denver, CO 80206 USA
关键词
asthma; fluticasone propionate; health care utilization; inhaled corticosteroid; pulmonary function;
D O I
10.1081/JAS-100001495
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
The impact of switching from other inhaled corticosteroids to fluticasone propionate was studied in patients with severe oral-steroid-dependent asthma over a 1-year period. In this open-label prospective study, patients on maintenance doses of oral and inhaled steroids were referred to a national asthma treatment center and were switched from their previous inhaled corticosteroid to fluticasone propionate 880 mug BID. Compared with data collected from the year prior to enrollment, treatment with fluticasone propionate resulted in significant improvements in pulmonary function, oral steroid requirements, and health resource utilization. In addition, five patients were completely weaned off oral steroids.
引用
收藏
页码:405 / 412
页数:8
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