LIAN 3.0: detecting linkage disequilibrium in multilocus data

被引：465

作者：

Haubold, B

Hudson, RR

机构：

[1] Max Planck Inst Chem Okol, D-07745 Jena, Germany

[2] Univ Chicago, Dept Ecol & Evolut, Chicago, IL 60637 USA

来源：

BIOINFORMATICS | 2000年 / 16卷 / 09期

关键词：

D O I：

10.1093/bioinformatics/16.9.847

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

LIAN is a program to test the null hypothesis of linkage equilibrium for multilocus data. LIAN incorporates both a Monte Carlo method as well as a novel algebraic method to carry out the hypothesis test. The program further returns the genetic diversity of the sample and the pairwise distances between its members.

引用

页码：847 / 848

页数：2

共 9 条

[1]

BROWN AHD, 1980, GENETICS, V96, P523

[2] The relative contributions of recombination and mutation to the divergence of clones of Neisseria meningitidis [J].