Value of Toxoplasma gondii detection in one hundred thirty-three placentas for the diagnosis of congenital toxoplasmosis

被引:22
作者
Fricker-Hidalgo, Helene
Brenier-Pinchart, Marie-Pierre
Schaal, Jean-Patrick
Equy, Veronique
Bost-Bru, Cecile
Pelloux, Herve
机构
[1] Ctr Hosp Univ, Serv Parasitol Mycol, F-38043 Grenoble, France
[2] Ctr Hosp Univ, Dept Agents Infect, Serv Parasitol Mycol, F-38043 Grenoble, France
[3] Ctr Hosp Univ, Dept Obstet Gynecol, F-38043 Grenoble, France
[4] Ctr Hosp Univ, Dept Pediat, F-38043 Grenoble, France
关键词
congenital toxoplasmosis; placenta; PCR; mouse inoculation;
D O I
10.1097/INF.0b013e318123e8d3
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The placenta examination by polymerase chain reaction and mouse inoculation increased the sensitivity of the diagnosis of congenital toxoplasmosis at birth from 60% (use of serologic techniques on the newborn's blood only) to 75% (both serologic techniques and placental analysis). The specificity of Toxoplasma gondii detection in the placenta was 94.7%.
引用
收藏
页码:845 / 846
页数:2
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