Molecular imaging of cancer: Applications of magnetic resonance methods

被引：15

作者：

Gimi, B ^{[1
]}

Pathak, AP ^{[1
]}

Ackerstaff, E ^{[1
]}

Glunde, K ^{[1
]}

Artemov, D ^{[1
]}

Bhujwalla, ZM ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, In Vivo Cellular Mol Imaging Ctr Program, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21205 USA

来源：

PROCEEDINGS OF THE IEEE | 2005年 / 93卷 / 04期

关键词：

cancer; metabolism; molecular imaging; magnetic resonance imaging (MRI); magnetic resonance spectroscopic imaging (MRSI); receptor expression; vascular imaging;

D O I：

10.1109/JPROC.2005.844266

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Cancer is a complex disease exhibiting a host of phenotypic diversities. Noninvasive multinuclear magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI) provide an array of capabilities to characterize and understand several of the vascular, metabolic, and physiological characteristics unique to cancer The availability of targeted contrast agents has widened the scope of MR techniques to include the detection of receptor and gene expression. In this paper, we have highlighted the application of several MR techniques in imaging and understanding cancer.

引用

页码：784 / 799

页数：16

共 149 条

[1]

Aboagye EO, 1998, CANCER RES, V58, P4075

[2]

Aboagye EO, 1999, CANCER RES, V59, P80

[3]

Abramovitch R, 1999, CANCER RES, V59, P5012

[4] Choline phospholipid metabolism: A target in cancer cells? [J].

Ackerstaff, E ;

Glunde, K ;

Bhujwalla, ZM .

JOURNAL OF CELLULAR BIOCHEMISTRY, 2003, 90 (03) :525-533

[5] Apoptosis is associated with triacyglycerol accumulation in Jurkat T-cells [J].

Al-Saffar, NMS ;

Titley, JC ;

Robertson, D ;

Clarke, PA ;

Jackson, LE ;

Leach, MO ;

Ronen, SM .

BRITISH JOURNAL OF CANCER, 2002, 86 (06) :963-970

[6]

Anderson SA, 2000, MAGNET RESON MED, V44, P433, DOI 10.1002/1522-2594(200009)44:3<433::AID-MRM14>3.0.CO

[7]

2-9

[8]

Aronen H J, 1993, Top Magn Reson Imaging, V5, P14

[9] CEREBRAL BLOOD-VOLUME MAPS OF GLIOMAS - COMPARISON WITH TUMOR GRADE AND HISTOLOGIC-FINDINGS [J].

ARONEN, HJ ;

GAZIT, IE ;

LOUIS, DN ;

BUCHBINDER, BR ;

PARDO, FS ;

WEISSKOFF, RM ;

HARSH, GR ;

COSGROVE, GR ;

HALPERN, EF ;

HOCHBERG, FH ;

ROSEN, BR .

RADIOLOGY, 1994, 191 (01) :41-51

[10] IN-VIVO SELECTIVE MEASUREMENT OF (1-C-13)-GLUCOSE METABOLISM IN TUMORS BY HETERONUCLEAR CROSS-POLARIZATION [J].

ARTEMOV, D ;

BHUJWALLA, ZM ;

GLICKSON, JD .

MAGNETIC RESONANCE IN MEDICINE, 1995, 33 (02) :151-155

← 1 2 3 4 5 6 7 8 9 10 →