Frequency of sample submission for optimal utilization of the cell culture cytotoxicity assay for detection of Clostridium difficile toxin

被引：24

作者：

Borek, AP ^{[1
]}

Aird, DZ ^{[1
]}

Carroll, KC ^{[1
]}

机构：

[1] Johns Hopkins Med Inst, Div Microbiol, Dept Pathol, Baltimore, MD 21287 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2005年 / 43卷 / 06期

关键词：

D O I：

10.1128/JCM.43.6.2994-2995.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We reviewed the results of repeated sample submissions within a 7-day time frame for Clostridium difficile toxin testing. A total of 2,940 samples were tested during a 3-month period using a cell culture cytotoxicity assay (CCCA). The results from all second samples (n = 1,101) were concordant with the original test result. In only two cases (0.8%; n = 247) was a third sample positive when the first two samples were negative. In this study, submission of multiple samples for CCCA did not increase detection of Clostridium difficile infection.

引用

页码：2994 / 2995

页数：2

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