RNA turnover: Unexpected consequences of being tailed

被引：38

作者：

Anderson, JT ^{[1
]}

机构：

[1] Marquette Univ, Dept Biol Sci, Milwaukee, WI 53201 USA

来源：

CURRENT BIOLOGY | 2005年 / 15卷 / 16期

关键词：

D O I：

10.1016/j.cub.2005.08.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In eukaryotic cells, the Tpoly(A) tails found on mRNA influence their stability and translation. The discovery of a second nuclear poly(A) polymerase complex has fueled a series of reports defining a new and unexpected role for 3'end poly(A) tails in the nuclear surveillance and turnover of noncoding RNAs and intergenic mRNAs of unknown function.

引用

页码：R635 / R638

页数：4

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