Metathesis-based synthesis of jasmonate and homojasmonate lactones, candidates for extracellular quorum sensing molecules in Candida albicans

被引：14

作者：

Cho, SC

Dussault, PH ^{[1
]}

Lisec, AD

Jensen, EC

Nickerson, KW

机构：

[1] Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA

[2] Univ Nebraska, Sch Biol Sci, Lincoln, NE 68588 USA

[3] St Johns Univ, Collegeville, MN 56321 USA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 02期

关键词：

D O I：

10.1039/a807417h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring-closing metathesis of jasmonate esters is shown to provide a rapid entry to jasmonate lactones. The lactones were investigated as possible quorum sensing molecules for the fungi Candida albicans. Assays demonstrated no effect on fungal morphology at concentrations up to 96 mu M.

引用

页码：193 / 196

页数：4

共 18 条

[1] [Anonymous], 1993, Natural Product Letters
[2] Armstrong SK, 1998, J CHEM SOC PERK T 1, P371
[3] PROPRIETES ET STRUCTURE DE LA CETOLACTONE C12H16O3 DE LESSENCE DE JASMIN ( JASMINUM GRANDIFLORUM L )
DEMOLE, E
WILLHALM, B
STOLL, M
[J]. HELVETICA CHIMICA ACTA, 1964, 47 (05) : 1152 - &
[4] Dussault P. H., 1996, CHEM ED, V1, P1
[5] QUORUM SENSING IN BACTERIA - THE LUXR-LUXI FAMILY OF CELL DENSITY-RESPONSIVE TRANSCRIPTIONAL REGULATORS
FUQUA, WC
WINANS, SC
GREENBERG, EP
[J]. JOURNAL OF BACTERIOLOGY, 1994, 176 (02) : 269 - 275
[6] Furstner A, 1997, SYNLETT, P1010
[7] RING-CLOSING METATHESIS AND RELATED PROCESSES IN ORGANIC-SYNTHESIS
GRUBBS, RH
MILLER, SJ
FU, GC
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1995, 28 (11) : 446 - 452
[8] KUENZLER P, 1978, HELV CHIM ACTA, V61, P2503
[9] NUTRITIONAL CONTROL OF DIMORPHISM IN CERATOCYSTIS-ULMI
KULKARNI, RK
NICKERSON, KW
[J]. EXPERIMENTAL MYCOLOGY, 1981, 5 (02): : 148 - 154
[10] LISEC AD, 1998, THESIS U NEBRASKA LI

← 1 2 →