Treatment of hyperinsulinaemic hypoglycaemia with nifedipine

被引：35

作者：

Eichmann, D ^{[1
]}

Hufnagel, M ^{[1
]}

Quick, P ^{[1
]}

Santer, R ^{[1
]}

机构：

[1] Univ Kiel, Childrens Hosp, D-24105 Kiel, Germany

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 1999年 / 158卷 / 03期

关键词：

nifedipine; hypoglycemia; hyperinsulinism; nesidioblastosis; persistent hyperinsulinaemic hypoglycaemia of infancy;

D O I：

10.1007/s004310051049

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We report on two children with mild persistent hyperinsulinaemic hypoglycaemia. In both, oral nifedipine treatment (0.7 and 2.0 mg/kg per day respectively) had a significant clinical effect. In one case, nifedipine monotherapy prevented hypoglycaemia; in the second case, the dosage and the side-effects of other substances could be reduced, thus circumventing surgical therapy. Conclusion Nifedipine treatment has a favourable effect on the clinical course of patients with mild hyperinsulinism. It represents a valuable new substance for the treatment of this disorder.

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收藏

页码：204 / 206

页数：3

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