Amyloid β vaccination:: reduced plaques and improved cognition

被引：40

作者：

Younkin, SG ^{[1
]}

机构：

[1] Mayo Clin Jacksonville, Ctr Neurosci, Jacksonville, FL 32224 USA

来源：

NATURE MEDICINE | 2001年 / 7卷 / 01期

关键词：

D O I：

10.1038/83292

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Studies in three different transgenic mouse models suggest that the amyloid beta -protein contributes to memory loss in Alzheimer disease. Immunization with an amyloid beta -peptide fragment reduces learning and memory impairments in mice, and this approach may eventually be used to prevent and/or treat this disease in people.

引用

页码：18 / 19

页数：2

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