Hormones to prevent coronary disease in women: When are observational studies adequate evidence?

被引:27
作者
Grady, D [1 ]
Hulley, SB [1 ]
机构
[1] Univ Calif San Francisco, Dept Epidemiol, San Francisco, CA 94105 USA
关键词
D O I
10.7326/0003-4819-133-12-200012190-00016
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Despite strong observational evidence from the Nurses' Health Study (including that reported by Grodstein and colleauges in this issue) and others, the disappointing results of three recent trials indicate that clinicians should not use hormone therapy for prevention of coronary disease until this practice is supported by evidence from randomized trials.
引用
收藏
页码:999 / 1001
页数:3
相关论文
共 17 条
[1]   INHIBITION OF CORONARY-ARTERY ATHEROSCLEROSIS BY 17-BETA ESTRADIOL IN OVARIECTOMIZED MONKEYS - LACK OF AN EFFECT OF ADDED PROGESTERONE [J].
ADAMS, MR ;
KAPLAN, JR ;
MANUCK, SB ;
KORITNIK, DR ;
PARKS, JS ;
WOLFE, MS ;
CLARKSON, TB .
ARTERIOSCLEROSIS, 1990, 10 (06) :1051-1057
[2]   POSTMENOPAUSAL ESTROGEN AND PREVENTION BIAS [J].
BARRETTCONNOR, E .
ANNALS OF INTERNAL MEDICINE, 1991, 115 (06) :455-456
[3]   ELEVATED SERUM-CHOLESTEROL IS A RISK FACTOR FOR BOTH CORONARY HEART-DISEASE AND THROMBOEMBOLIC STROKE IN HAWAIIAN JAPANESE MEN - IMPLICATIONS OF SHARED RISK [J].
BENFANTE, R ;
YANO, K ;
HWANG, LJ ;
CURB, JD ;
KAGAN, A ;
ROSS, W .
STROKE, 1994, 25 (04) :814-820
[4]  
CANNER PL, 1980, NEW ENGL J MED, V303, P1038
[5]  
Ettinger B, 1999, AM J MANAG CARE, V5, P779
[6]   THE RELATIONSHIP OF TREATMENT ADHERENCE TO THE RISK OF DEATH AFTER MYOCARDIAL-INFARCTION IN WOMEN [J].
GALLAGHER, EJ ;
VISCOLI, CM ;
HORWITZ, RI .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1993, 270 (06) :742-744
[7]   HORMONE-THERAPY TO PREVENT DISEASE AND PROLONG LIFE IN POSTMENOPAUSAL WOMEN [J].
GRADY, D ;
RUBIN, SM ;
PETITTI, DB ;
FOX, CS ;
BLACK, D ;
ETTINGER, B ;
ERNSTER, VL ;
CUMMINGS, SR .
ANNALS OF INTERNAL MEDICINE, 1992, 117 (12) :1016-1037
[8]   Postmenopausal estrogen and progestin use and the risk of cardiovascular disease [J].
Grodstein, F ;
Stampfer, MJ ;
Manson, JE ;
Colditz, GA ;
Willett, WC ;
Rosner, B ;
Speizer, FE ;
Hennekens, CH .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (07) :453-461
[9]   A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease [J].
Grodstein, F ;
Manson, JE ;
Colditz, GA ;
Willett, WC ;
Speizer, FE ;
Stampfer, MJ .
ANNALS OF INTERNAL MEDICINE, 2000, 133 (12) :933-941
[10]   Effects of estrogen replacement on the progression of coronary-artery atherosclerosis [J].
Herrington, DM ;
Reboussin, DM ;
Brosnihan, KB ;
Sharp, PC ;
Shumaker, SA ;
Snyder, TE ;
Furberg, CD ;
Kowalchuk, GJ ;
Stuckey, TD ;
Rogers, WJ ;
Givens, DH ;
Waters, D .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (08) :522-529