Biopharmaceutical availability of sulphadicramide from ocular ointments in vitro

被引：7

作者：

Grzeskowiak, E ^{[1
]}

机构：

[1] K Marcinkowski Univ Med Sci, Dept Chem Phys, Poznan, Poland

来源：

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES | 1998年 / 6卷 / 03期

关键词：

ophthalmic drug; sulphadicramide; permeability coefficient; biopharmaceutical; promoters; absorption;

D O I：

10.1016/S0928-0987(97)10006-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The effect of absorption promoters, i.e. sodium deoxycholate, lauryl ether polioxyethylene-9, and L-alpha-lysophosphatidylo choline, on the process of sulphadicramide dialysis through lipophilic synthetic membranes and animal cornea in vitro, was studied. Formulation of ophthalmic ointments containing sulphadicramide and the above promoters was proposed and biopharmaceutical evaluation of the ointments was performed. (C) 1998 Elsevier Science B.V.

引用

页码：247 / 253

页数：7

共 20 条

[1] INFLUENCE OF SOME PRESERVATIVES ON THE CORNEAL PERMEABILITY OF PILOCARPINE AND DEXAMETHASONE, INVITRO [J].