Hierarchically porous bioactive glass scaffolds synthesized with a PUF and P123 cotemplated approach

被引:101
作者
Li, Xia
Wang, Xiupeng
Chen, Hangrong
Jiang, Peng
Dong, Xiaoping
Shi, Jianlin [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China
[2] S China Univ Technol, Sch Mat Sci & Engn, Guangzhou 510641, Peoples R China
关键词
D O I
10.1021/cm0708564
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Hierarchically porous bioactive glass (CaO-SiO2-P2O5) scaffolds have been prepared by using nonionic block copolymer EO20PO70EO20 (P123) and polyurethane (PUF) as cotemplates. It exhibits a hierarchical structure with interconnected macropores (about 200-400 or 500-700 mu m), which provide the potential for tissue ingrowth and the neovascularization, and uniform mesopores (3.68 nm), which cause an increase in the specific surface area and enhanced bioactivity and release of ionic products. The ordered hierarchically porous scaffold has the advantages of both mesoporosity and macroporosity, which may find potential applications in tissue engineering and drug storage.
引用
收藏
页码:4322 / 4326
页数:5
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