Proton magnetic resonance spectroscopic imaging in pediatric pilomyxoid astrocytoma

被引：28

作者：

Cirak, B

Horska, A

Barker, PB

Burger, PC

Carson, BS

Avellino, AM

机构：

[1] Johns Hopkins Med Inst, Dept Neurosurg, Div Pediat Neurosurg, Baltimore, MD 21205 USA

[2] Johns Hopkins Univ, Russell H Morgan Dept Radiol & Radiol Sci, Div Neuroradiol, Baltimore, MD USA

[3] Kennedy Krieger Inst, Baltimore, MD USA

[4] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21205 USA

[5] Johns Hopkins Med Inst, Dept Neurosurg, Div Pediat, Baltimore, MD 21205 USA

来源：

CHILDS NERVOUS SYSTEM | 2005年 / 21卷 / 05期

关键词：

pediatric brain tumor; pilocytic astrocytoma; pilomyxoid astrocytoma; proton magnetic resonance spectroscopy;

D O I：

10.1007/s00381-004-1023-2

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objects: A pilomyxoid astrocytoma (PmA) is considered to be either a more aggressive variant of a pediatric pilocytic astrocytoma (PA) or a tumor of a separate entity. Methods: We present two cases of pediatric optic-chiasmatic PmA. Proton magnetic resonance spectroscopic imaging (MRSI) of the PmA revealed decreased concentrations of total choline (Cho), creatine (Cr), and N-acetyl aspartate (NAA). In contrast, proton MR spectra of PAs showed elevated Cho and decreased Cr and NAA signals. Conclusion: Low metabolite concentrations in PmAs detected by MRSI may therefore help to distinguish PmAs from PAs preoperatively.

引用

页码：404 / 409

页数：6

共 19 条

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