Characterizing the elastic properties of tissues

被引：280

作者：

Akhtar, Riaz ^{[1
,2
]}

Sherratt, Michael J. ^{[3
]}

Cruickshank, J. Kennedy ^{[2
]}

Derby, Brian ^{[1
]}

机构：

[1] Univ Manchester, Sch Mat, Manchester M1 7HS, Lancs, England

[2] Univ Manchester, Manchester Acad Hlth Sci Ctr, Cardiovasc Sci Res Grp, Manchester M13 9NT, Lancs, England

[3] Univ Manchester, Manchester Acad Hlth Sci Ctr, Manchester M13 9PL, Lancs, England

来源：

MATERIALS TODAY | 2011年 / 14卷 / 03期

基金：

英国惠康基金;

关键词：

PULSE-WAVE VELOCITY; SMALL-RESISTANCE ARTERIES; MECHANICAL-PROPERTIES; AORTIC STIFFNESS; STRUCTURAL ALTERATIONS; ACOUSTIC MICROSCOPE; RENAL-FAILURE; AGE; COLLAGEN; NANOINDENTATION;

D O I：

10.1016/S1369-7021(11)70059-1

中图分类号：

T [工业技术];

学科分类号：

120111 [工业工程];

摘要：

The quality of life of ageing populations is increasingly determined by age-related changes to the mechanical properties of numerous biological tissues. Degradation and mechanical failure of these tissues has a profound effect on human morbidity and mortality. Soft tissues have complex and intricate structures and, similar to engineering materials, their mechanical properties are controlled by their microstructure. Thus age-relate changes in mechanical behavior are determined by changes in the properties and relative quantities of microstructural tissue components. This review focuses on the cardiovascular system; it discusses the techniques used both in vivo and ex vivo to determine the age-related changes in the mechanical properties of arteries.

引用

页码：96 / 105

页数：10

共 98 条

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