Clinical and Microbiological Features of a Cystic Fibrosis Patient Chronically Colonized with Pandoraea sputorum Identified by Combining 16S rRNA Sequencing and Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry

被引：27

作者：

Fernandez-Olmos, A. ^{[1
,2
,3
]}

Morosini, M. I. ^{[1
,2
,3
]}

Lamas, A. ^{[3
,4
]}

Garcia-Castillo, M. ^{[1
,2
,3
]}

Garcia-Garcia, L. ^{[1
,2
,3
]}

Canton, R. ^{[1
,2
,3
]}

Maiz, L. ^{[3
,4
]}

机构：

[1] IRYCIS, Microbiol Serv, Madrid, Spain

[2] IRYCIS, CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain

[3] Hosp Univ Ramon & Cajal, Madrid, Spain

[4] IRYCIS, Unidad Fibrosis Quist, Madrid, Spain

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 03期

关键词：

APISTA; INFECTIONS;

D O I：

10.1128/JCM.05730-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Clonal isolates identified as various nonfermentative Gram-negative bacilli over a 5-year period from sputum cultures of a 30-year-old cystic fibrosis patient were successfully reidentified as Pandoraea sputorum by combining 16S rRNA sequencing and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). Decreased lung function improved after 1 year of azithromycin and inhaled 7%-hypertonic saline treatment.

引用

页码：1096 / 1098

页数：3

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