Phagocytosis of Vibrio cholerae O139 Bengal by human polymorphonuclear leukocytes

被引：5

作者：

Albert, MJ

Qadri, F

Bhuiyan, NA

Ahmad, SM

Ansaruzzaman, M

Weintraub, A

机构：

[1] Int Ctr Diarrhoeal Dis Res B, Div Sci Lab, Dhaka 1000, Bangladesh

[2] Huddinge Hosp, Karolinska Inst, Dept Immunol Microbiol Pathol & Infect Dis, Div Clin & Oral Bacteriol, S-14186 Huddinge, Sweden

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 1999年 / 6卷 / 02期

关键词：

D O I：

10.1128/CDLI.6.2.276-278.1999

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Capsulated bacteria exhibit serum (complement) resistance and resistance to phagocytosis, which result in disseminated infections. Vibrio cholerae O139 strains possess a thin capsule and have been found to be partially serum resistant in a previous study. In the present study, compared to a standard capsulated Klebsiella pneumoniae strain, which showed total resistance to killing by phagocytosis, V. cholerae O139 strains were shown to be only partially resistant, with most strains showing <40% survival. These findings may explain the relative rarity of V. cholerae O139 bacteremia in cholera caused by this organism.

引用

收藏

页码：276 / 278

页数：3

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