Mutations of sodium channels in periodic paralysis -: Can they explain the disease and predict treatment?

被引:6
作者
Griggs, RC
Ptácek, LJ
机构
[1] Univ Rochester, Sch Med & Dent, Dept Neurol, Rochester, NY 14642 USA
[2] Univ Utah, Dept Neurol, Salt Lake City, UT 84112 USA
关键词
D O I
10.1212/WNL.52.7.1309
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
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页码:1309 / 1310
页数:2
相关论文
共 8 条
[1]  
CANNON SC, 1998, MOL NEUROLOGY, P257
[2]   Impaired slow inactivation in mutant sodium channels [J].
Cummins, TR ;
Sigworth, FJ .
BIOPHYSICAL JOURNAL, 1996, 71 (01) :227-236
[3]  
Hans M, 1999, J NEUROSCI, V19, P1610
[4]   Defective slow inactivation of sodium channels contributes to familial periodic paralysis [J].
Hayward, LJ ;
Sandoval, GM ;
Cannon, SC .
NEUROLOGY, 1999, 52 (07) :1447-1453
[5]   Channelopathies: Ion channel disorders of muscle as a paradigm for paroxysmal disorders of the nervous system [J].
Ptacek, LJ .
NEUROMUSCULAR DISORDERS, 1997, 7 (04) :250-255
[6]  
PTACEK LJ, 1991, CELL, V67, P1021
[7]  
ROJAS CV, 1991, NATURE, V354, P387, DOI 10.1038/354387a0
[8]   SLOW NA+ CHANNEL INACTIVATION MUST BE DISRUPTED TO EVOKE PROLONGED DEPOLARIZATION-INDUCED PARALYSIS [J].
RUFF, RL .
BIOPHYSICAL JOURNAL, 1994, 66 (02) :542-542