Total Ischemic Time The Correct Focus of Attention for Optimal ST-Segment Elevation Myocardial Infarction Care

被引：105

作者：

Denktas, Ali E.

Anderson, H. Vernon

McCarthy, James

Smalling, Richard W.

机构：

[1] Univ Texas Houston, Hlth Sci Ctr Houston, Houston, TX USA

[2] Mem Hermann Heart & Vasc Inst, Houston, TX USA

来源：

JACC-CARDIOVASCULAR INTERVENTIONS | 2011年 / 4卷 / 06期

关键词：

coronary angioplasty; ischemic time; myocardial infarction; pre-hospital fibrinolysis; reperfusion; STEMI; PERCUTANEOUS CORONARY INTERVENTION; TO-BALLOON TIME; PREHOSPITAL THROMBOLYSIS; PRIMARY ANGIOPLASTY; SYMPTOM-ONSET; IMMEDIATE ANGIOPLASTY; STANDARD THERAPY; MORTALITY; DELAY; REPERFUSION;

D O I：

10.1016/j.jcin.2011.02.012

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Currently accepted standards for gauging quality of care in the treatment of ST-segment elevation myocardial infarction (STEMI) mainly focus on shortening the time to treatment after the patient arrives at the hospital. But this narrow focus fails to consider the substantial duration of myocardial ischemia that exists prior to hospital arrival, and the large number of deaths that occur during the pre-hospital period. The time from symptom onset until reperfusion occurs is one estimate of total ischemic time. Several experimental studies and now human clinical studies have confirmed that infarct size and mortality are strongly correlated with the total ischemic time, and much less so with its subintervals like door-to-balloon time. This review will discuss the importance of total ischemic time in STEMI. (J Am Coll Cardiol Intv 2011;4:599-604) (C) 2011 by the American College of Cardiology Foundation

引用

收藏

页码：599 / 604

页数：6

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