Tissue-specific congener composition of organohalogen and metabolite contaminants in East Greenland polar bears (Ursus maritimus)

被引：117

作者：

Gebbink, Wouter A. ^{[1
,2
]}

Sonne, Christian ^{[3
]}

Dietz, Rune ^{[3
]}

Kirkegaard, Maja ^{[3
]}

Riget, Frank F. ^{[3
]}

Born, Erik W. ^{[4
]}

Muir, Derek C. G. ^{[5
]}

Letcher, Robert J. ^{[1
,2
]}

机构：

[1] Carleton Univ, Natl Wildlife Res Ctr, Sci & Technol Branch, Ottawa, ON K1S 5B6, Canada

[2] Carleton Univ, Dept Chem, Ottawa, ON K1S 5B6, Canada

[3] Univ Aarhus, Natl Environm Res Inst, Dept Artic Environm, DK-4000 Roskilde, Denmark

[4] Greenland Inst Nat Resources, DK-3900 Nuuk, Greeland, Denmark

[5] Environm Canada, Water Sci & Technol Directorate, Burlington, ON L7R 4A6, Canada

来源：

ENVIRONMENTAL POLLUTION | 2008年 / 152卷 / 03期

基金：

加拿大自然科学与工程研究理事会;

关键词：

polar bear; brominated and chlorinated contaminants; metabolites; tissue-specific congener composition; East Greenland;

D O I：

10.1016/j.envpol.2007.07.001

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Congener patterns of the major organohalogen contaminant classes of PCBs, PBDEs and their metabolites and/or by-products (OH-PCBs, MeSO2-PCBs, OH-PBDEs and MeO-PBDEs) were examined in adipose tissue, liver, brain and blood of East Greenland polar bears (Ursus maritimus). PCB, OH-PCB, MeSO2-PCB and PBDE congener patterns showed significant differences (p <= 0.05) mainly in the liver and the brain relative to the adipose tissue and the blood. OH-PBDEs and MeO-PBDEs were not detected in the brain and liver, but had different patterns in blood versus the adipose tissue. Novel OH-polybrominated biphenyls (OH-PBBs), one tri- and two tetra-brominated OH-PBBs were detected in all tissues and blood. Congener pattern differences among tissues and blood are likely due to a combination of factors, e.g., biotransformation and retention in the liver, retention in the blood and blood-brain barrier transport. Our findings suggest that different congener pattern exposures to these classes of contaminants should be considered with respect to potential target tissue-specific effects in East Greenland polar bears. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：621 / 629

页数：9

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