Immune information, self-organization and meaning

被引:107
作者
Atlan, H
Cohen, IR [1 ]
机构
[1] Weizmann Inst Sci, Dept Immunol, IL-76100 Rehovot, Israel
[2] Hadassah Univ Hosp, Human Biol Res Ctr, IL-91120 Jerusalem, Israel
关键词
context; information; language; meaning; redundancy; self-organization;
D O I
10.1093/intimm/10.6.711
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
To effect the molecular integrity of the individual, the immune system has to gather antigenic information and respond in a meaningful way. Immunologists traditionally have focused their research on analyzing the component parts of the system. The achievements of immunology in its analytical enterprise have now made it possible to begin the task of synthesis. In this paper, we shall consider how the immune system combines germline and somatic information using a chemical language to establish the functional meaning of antigens.
引用
收藏
页码:711 / 717
页数:7
相关论文
共 27 条
[1]  
[Anonymous], 1969, SELF NOT SELF
[2]   SELF CREATION OF MEANING [J].
ATLAN, H .
PHYSICA SCRIPTA, 1987, 36 (03) :563-576
[3]   FORMAL DEFINITION OF ORGANIZATION [J].
ATLAN, H .
JOURNAL OF THEORETICAL BIOLOGY, 1974, 45 (02) :295-304
[4]  
Atlan H., 1972, L'organisation biologique et la theorie de l'information
[5]  
ATLAN H, 1983, CYBERNETICS THEORY A, P9
[6]  
AVRAMEAS S, 1991, IMMUNOL TODAY, V12, P154
[7]  
BURNET FM, 1959, CLONAL SELECTION THE
[8]   THE COGNITIVE PARADIGM AND THE IMMUNOLOGICAL HOMUNCULUS [J].
COHEN, IR .
IMMUNOLOGY TODAY, 1992, 13 (12) :490-494
[9]   THE COGNITIVE PRINCIPLE CHALLENGES CLONAL SELECTION [J].
COHEN, IR .
IMMUNOLOGY TODAY, 1992, 13 (11) :441-444
[10]  
COHEN IR, 1995, ISRAEL J MED SCI, V31, P36