What is a moment? "Cortical" sensory integration over a brief interval

被引:81
作者
Hopfield, IJ [1 ]
Brody, CD
机构
[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA
[2] NYU, Ctr Neural Sci, New York, NY 10003 USA
关键词
D O I
10.1073/pnas.250483697
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Recognition of complex temporal sequences is a general sensory problem that requires integration of information over time. We describe a very simple "organism" that performs this task, exemplified here by recognition of spoken monosyllables. The network's computation can be understood through the application of simple but generally unexploited principles describing neural activity. The organism is a network of very simple neurons and synapses; the experiments are simulations. The network's recognition capabilities are robust to variations across speakers, simple masking noises, and targe Variations in system parameters. The network principles underlying recognition of short temporal sequences are applied here to speech, but similar ideas can be applied to aspects of vision, touch, and olfaction. In this article, we describe only properties of the system that could be measured if it were a real biological organism. We delay publication of the principles behind the network's operation as an intellectual challenge: the essential principles of operation can be deduced based on the experimental results presented here alone. An interactive web site (http:// neuron.princeton.edu/similar to moment) is available to allow readers to design and carry out their own experiments on the organism.
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页码:13919 / 13924
页数:6
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