Adherence to vascular protection drugs in diabetic patients in Quebec: a population-based analysis

被引：5

作者：

Asghari, Shabnam ^{[1
]}

Courteau, Josiane ^{[1
]}

Drouin, Catherine ^{[1
]}

Gregoire, Jean-Pierre ^{[2
,3
]}

Carpentier, Andre C. ^{[4
]}

Paquet, Mariane ^{[5
]}

Vanasse, Alain ^{[1
,6
]}

机构：

[1] CHUS, PRIMUS Grp, Ctr Rech Clin Etienne Le Bel, Sherbrooke, PQ, Canada

[2] Univ Laval, Fac Pharm, Quebec City, PQ, Canada

[3] Univ Laval, Populat Hlth Res Unit, Quebec City, PQ, Canada

[4] Univ Sherbrooke, Fac Med & Hlth Sci, Dept Med, Sherbrooke, PQ J1H 5N4, Canada

[5] Univ Montreal, Dept Social & Prevent Med, Montreal, PQ H3C 3J7, Canada

[6] Univ Sherbrooke, Fac Med & Hlth Sci, Dept Family Med, Sherbrooke, PQ J1H 5N4, Canada

来源：

DIABETES & VASCULAR DISEASE RESEARCH | 2010年 / 7卷 / 02期

关键词：

adherence; diabetes; medical record; medication use; vascular protection;

D O I：

10.1177/1479164109360593

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

The purpose of this study was to assess adherence to vascular protection drugs in diabetic patients using a cohort of diabetic patients aged >= 30 years, covered by the public drug insurance in the province of Quebec, excluding gestational diabetes and patients who were hopitalized or died during the 1-year follow-up. Drug adherence was measured using the medication possession ratio. Multivariate analyses, including logit and multinomial logit were used. Of the 170,381 diabetics (mean age: 62 +/- 14 years), 18% and 32% were regular users of ASA and ACEIs/ARBs, respectively. Regular use increased with age (p < 0.0001) and comorbidities (p < 0.0001). Rural inhabitants were more likely to use ACEIs/ARBs (OR: 1.29; 95% CI: 1.26-1.32) and to be regular users (OR: 1.36; 95% CI: 1.32-1.39). Similar results were found for ASA. In conclusion, despite the high cardiovascular risks associated with diabetes, less than one-third of diabetic adults took vascular-protection drugs regularly. This important issue needs proper attention.

引用

页码：167 / 171

页数：5

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