Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1 to 6q

被引：30

作者：

Watanabe, TK

Fujiwara, T

Shimizu, F

Okuno, S

Suzuki, M

Takahashi, E

Nakamura, Y

Hirai, Y

机构：

[1] OTSUKA PHARMACEUT CO LTD,OTSUKA GEN RES INST,TOKUSHIMA 77101,JAPAN

[2] UNIV TOKYO,INST MED SCI,MOLEC MED LAB,TOKYO,JAPAN

[3] TOTTORI UNIV,FAC MED,SCH LIFE SCI,DEPT MOLEC & CELL GENET,YONAGO,TOTTORI,JAPAN

来源：

CYTOGENETICS AND CELL GENETICS | 1996年 / 73卷 / 1-2期

关键词：

D O I：

10.1159/000134329

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

From a human fetal-brain cDNA library we isolated a putative human homologue of the murine Tcte1 gene. The cDNA, designated TCTEL1, contained an open reading frame of 339 nucleotides encoding 113 amino acids. The predicted peptides of TCTEL1 showed 94% and 55% identity (100% and 94% similarity) with those of murine Tcte1 and human RP3. Northern-blot analysis revealed a 0.9-kb transcript in all tissues examined. This gene was mapped by FISH to chromosome bands 6q25.2-->q25.3, the syntenic region of the murine t-complex locus of chromosome 17.

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页码：153 / 156

页数：4

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