Genetics -: Influence of TOR kinase on lifespan in C-elegans

被引:832
作者
Vellai, T [1 ]
Takacs-Vellai, K
Zhang, Y
Kovacs, AL
Orosz, L
Müller, F
机构
[1] Univ Fribourg, Dept Biol, CH-1700 Fribourg, Switzerland
[2] Eotvos Lorand Univ, Dept Gen Zool, H-1117 Budapest, Hungary
[3] Eotvos Lorand Univ, Dept Genet, H-1117 Budapest, Hungary
[4] Agr Biotechnol Ctr, H-2100 Godollo, Hungary
关键词
D O I
10.1038/426620a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
[No abstract available]
引用
收藏
页码:620 / 620
页数:1
相关论文
共 11 条
[1]   Identification of TOR signaling complexes: more TORC for the cell growth engine [J].
Abraham, RT .
CELL, 2002, 111 (01) :9-12
[2]   Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes [J].
Ashrafi, K ;
Chang, FY ;
Watts, JL ;
Fraser, AG ;
Kamath, RS ;
Ahringer, J ;
Ruvkun, G .
NATURE, 2003, 421 (6920) :268-272
[3]   Rates of behavior and aging specified by mitochondrial function during development [J].
Dillin, A ;
Hsu, AL ;
Arantes-Oliveira, NA ;
Lehrer-Graiwer, J ;
Hsin, H ;
Fraser, AG ;
Kamath, RS ;
Ahringer, J ;
Kenyon, C .
SCIENCE, 2002, 298 (5602) :2398-2401
[4]   Timing requirements for insulin/IGF-1 signaling in C-elegans [J].
Dillin, A ;
Crawford, DK ;
Kenyon, C .
SCIENCE, 2002, 298 (5594) :830-834
[5]   A C-ELEGANS MUTANT THAT LIVES TWICE AS LONG AS WILD-TYPE [J].
KENYON, C ;
CHANG, J ;
GENSCH, E ;
RUDNER, A ;
TABTIANG, R .
NATURE, 1993, 366 (6454) :461-464
[6]  
KENYON C, 1997, C ELEGANS, V2, P701
[7]   TOR deficiency in C-elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation [J].
Long, XM ;
Spycher, C ;
Han, ZS ;
Rose, AM ;
Müller, F ;
Avruch, J .
CURRENT BIOLOGY, 2002, 12 (17) :1448-1461
[8]   Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control [J].
Oldham, S ;
Hafen, E .
TRENDS IN CELL BIOLOGY, 2003, 13 (02) :79-85
[9]  
Riddle D. L., 1997, C ELEGANS, P739
[10]   Insulin signalling and the regulation of glucose and lipid metabolism [J].
Saltiel, AR ;
Kahn, CR .
NATURE, 2001, 414 (6865) :799-806