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A 65-kilobase pathogenicity island is unique to philadelphia-1 strains of Legionella pneumophila

被引：49
作者：
Brassinga, AKC
Hiltz, MF
Sisson, GR
Morash, MG
Hill, N
Garduno, E
Edelstein, PH
Garduno, RA
Hoffman, PS
机构：
[1] Dalhousie Univ, Dept Microbiol & Immunol, Halifax, NS B3H 4H7, Canada
[2] Dalhousie Univ, Fac Med, Dept Med, Div Infect Dis, Halifax, NS B3H 4H7, Canada
[3] Univ Penn, Med Ctr, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
来源：
JOURNAL OF BACTERIOLOGY | 2003年 / 185卷 / 15期
关键词：
D O I：
10.1128/JB.185.15.4630-4637.2003
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Nucleotide sequence analysis of an similar to80-kb genomic region revealed an similar to65-kb locus that bears hallmarks of a pathogenicity island. This locus includes homologues of a type IV secretion system, mobile genetic elements, and known virulence factors. Comparative studies with other Legionella pneumophila strains and serogroups indicated that this similar to65-kb locus is unique to L. pneumophila serogroup 1 Philadelphia-1 strains.
引用
收藏
页码：4630 / 4637
页数：8
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