Enhancement of solution NMR and MRI with laser-polarized xenon

被引：320

作者：

Navon, G

Song, YQ

Room, T

Appelt, S

Taylor, RE

Pines, A

机构：

[1] UNIV CALIF BERKELEY,DEPT CHEM,BERKELEY,CA 94720

[2] UNIV CALIF BERKELEY,LAWRENCE BERKELEY NATL LAB,DIV SCI MAT,BERKELEY,CA 94720

[3] TEL AVIV UNIV,SCH CHEM,IL-69978 TEL AVIV,ISRAEL

来源：

SCIENCE | 1996年 / 271卷 / 5257期

关键词：

D O I：

10.1126/science.271.5257.1848

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Optical pumping with laser light can be used to polarize the nuclear spins of gaseous xenon-129. When hyperpolarized xenon-129 is dissolved in liquids, a time-dependent departure of the proton spin polarization from its thermal equilibrium is observed, The variation of the magnetization is an unexpected manifestation of the nuclear Overhauser effect, a consequence of cross-relaxation between the spins of solution protons and dissolved xenon-129. Time-resolved magnetic resonance images of both nuclei in solution show that the proton magnetization is selectively perturbed in regions containing spin-polarized xenon-129. This effect could find use in nuclear magnetic resonance spectroscopy of surfaces and proteins and in magnetic resonance imaging.

引用

页码：1848 / 1851

页数：4

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