Meiotic recombination: Making and breaking go hand in hand

被引:22
作者
Baudat, F [1 ]
Keeney, S [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA
关键词
D O I
10.1016/S0960-9822(01)00013-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Accurate segregation of homologous chromosomes at the first meiotic division requires the tight coordination of DNA replication, homologous recombination and chromosome organization. Recent studies suggest that the initiation of meiotic recombination is mechanistically coupled to premeiotic DNA replication.
引用
收藏
页码:R45 / R48
页数:4
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