Lipase-catalyzed glucose fatty acid ester synthesis in ionic liquids

被引：129

作者：

Ganske, F ^{[1
]}

Bornscheuer, UT ^{[1
]}

机构：

[1] Univ Greifswald, Inst Chem & Biochem, Dept Tech Chem & Biotechnol, D-17487 Greifswald, Germany

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 14期

关键词：

D O I：

10.1021/ol0511169

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Glucose fatty acid ester synthesis with poly(ethylene glycol)-modified Candida antarctica lipase B (CAL-B) was performed in pure 1-butyl-3-methyl imidazolium tetrafluoroborate [BMIM][BF4] (30% conversion) and in pure 1-butyl-3-methyl imidazolium hexafluorophosphate [BMIM]-[PF6] (35% conversion). In a solvent system composed of ionic liquid and 40% t-BuOH conversions up to 90% and isolated yields of up to 89% were achieved using fatty acid vinyl esters as acyl donors and commercial CAL-B.

引用

页码：3097 / 3098

页数：2

共 20 条

[1] ENZYME CATALYZED PREPARATION OF 6-O-ACYLGLUCOPYRANOSIDES [J].

ADELHORST, K ;

BJORKLING, F ;

GODTFREDSEN, SE ;

KIRK, O .

SYNTHESIS-STUTTGART, 1990, (02) :112-115

[2] SYNTHESIS OF FATTY ESTERS BY POLYETHYLENE GLYCOL-MODIFIED LIPASE [J].

BASRI, M ;

AMPON, K ;

ZIN, WM ;

YUNUS, W ;

RAZAK, CNA ;

SALLEH, AB .

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 1995, 64 (01) :10-16

[3] THE FUTURE-IMPACT OF INDUSTRIAL LIPASES [J].

BJORKLING, F ;

GODTFREDSEN, SE ;

KIRK, O .

TRENDS IN BIOTECHNOLOGY, 1991, 9 (10) :360-363

[4]

Cao LQ, 1996, FETT-LIPID, V98, P332

[5] Lipase-catalyzed solid-phase synthesis of sugar esters. Influence of immobilization on productivity and stability of the enzyme [J].

Cao, LQ ;

Bornscheuer, UT ;

Schmid, RD .

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 1999, 6 (03) :279-285

[6] Lipase-catalyzed solid phase synthesis of sugar fatty acid esters [J].

Cao, LQ ;

Fischer, A ;

Bornscheuer, UT ;

Schmid, RD .

BIOCATALYSIS AND BIOTRANSFORMATION, 1997, 14 (04) :269-283

[7] Lipase-catalyzed solid-phase synthesis of sugar esters, IV: Selectivity of lipases towards primary and secondary hydroxyl groups in carbohydrates [J].

Cao, LQ ;

Bornscheuer, UT ;

Schmid, RD .

BIOCATALYSIS AND BIOTRANSFORMATION, 1998, 16 (04) :249-257

[8]

Cull SG, 2000, BIOTECHNOL BIOENG, V69, P227

[9] ENZYMATIC SOLVENT-FREE SYNTHESIS OF SUGAR ACETAL FATTY-ACID ESTERS [J].

FREGAPANE, G ;

SARNEY, DB ;

VULFSON, EN .

ENZYME AND MICROBIAL TECHNOLOGY, 1991, 13 (10) :796-800

[10] LIPASE-CATALYZED ACYLATION OF SUGARS SOLUBILIZED IN HYDROPHOBIC SOLVENTS BY COMPLEXATION [J].

IKEDA, I ;

KLIBANOV, AM .

BIOTECHNOLOGY AND BIOENGINEERING, 1993, 42 (06) :788-791

← 1 2 →