Persistent hepatitis associated with chronic active Epstein-Barr virus infection

被引:18
作者
Yuge, A
Kinoshita, E
Moriuchi, M
Ohno, Y
Haga, H
Moriuchi, H
机构
[1] Nagasaki Univ Hosp, Dept Pediat, Nagasaki 8528501, Japan
[2] Nagasaki Univ Hosp, Dept Surg 2, Nagasaki, Japan
[3] Nagasaki Univ, Grad Sch Biomed Sci, Dept Mol Microbiol & Immunol, Nagasaki, Japan
[4] Kyoto Univ Hosp, Dept Pathol, Kyoto 606, Japan
关键词
hepatitis; Epstein-Barr virus; real time polymerase chain reaction; liver biopsy; in situ hybridization;
D O I
10.1097/01.inf.0000105182.51471.4b
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A previously healthy boy developed persistent hepatitis without fever or lymphoproliferative disorder. Although serologic tests were not indicative, Epstein-Barr virus (EBV) genome and transcripts were detected from the liver tissue, and real time PCR detected extremely high levels of EBV viremia. EBV infection should be included in the differential diagnoses of hepatitis of unknown etiology, even with unremarkable serologic data.
引用
收藏
页码:74 / 76
页数:3
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