Early chronic obstructive pulmonary disease: definition, assessment, and prevention

被引:243
作者
Rennard, Stephen I. [1 ]
Drummond, M. Bradley [2 ]
机构
[1] Univ Nebraska Med Ctr, Nebraska Med Ctr, Dept Internal Med, Omaha, NE 69198 USA
[2] Johns Hopkins Univ, Sch Med, Baltimore, MD USA
基金
美国国家卫生研究院;
关键词
AIR-FLOW OBSTRUCTION; QUALITY-OF-LIFE; LUNG-FUNCTION; RISK-FACTORS; CIGARETTE-SMOKING; NATURAL-HISTORY; OSCILLATORY IMPEDANCE; PHYSICAL-ACTIVITY; PARENTAL SMOKING; NHLBI WORKSHOP;
D O I
10.1016/S0140-6736(15)60647-X
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. COPD, however, is a heterogeneous collection of diseases with differing causes, pathogenic mechanisms, and physiological effects. Therefore a comprehensive approach to COPD prevention will need to address the complexity of COPD. Advances in the understanding of the natural history of COPD and the development of strategies to assess COPD in its early stages make prevention a reasonable, if ambitious, goal.
引用
收藏
页码:1778 / 1788
页数:11
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