ERG and anatomical abnormalities suggesting retinopathy in dementia with Lewy bodies

被引:48
作者
Devos, D
Tir, M
Maurage, CA
Waucquier, N
Defebvre, L
Defoort-Dhellemmes, S
Destée, A
机构
[1] Ctr Hosp Univ Lille, Serv Neurol & Pathol Mouvement, EA2683, MENRT, Lille, France
[2] Ctr Hosp Univ Lille, Neuroophthalmol Serv, CNRS, Lille, France
[3] Ctr Hosp Univ Lille, Serv Anat Pathol, INSERM, U422, Lille, France
关键词
D O I
10.1212/01.wnl.0000178896.44905.33
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors used flash electroretinography to demonstrate dysfunction of the photopic and scotopic retina in patients with dementia with Lewy bodies and visual hallucinations (VHs) compared with patients with Parkinson disease, patients without VHs, and controls. The retinal dysfunction may be related to slight alteration of the photoreceptors and numerous pale inclusions in the outer plexiform layer found at the post mortem examination, suggesting a specific retinopathy.
引用
收藏
页码:1107 / 1110
页数:4
相关论文
共 11 条
[1]  
Ballard C, 2000, ANN NEUROL, V48, P868, DOI 10.1002/1531-8249(200012)48:6<868::AID-ANA7>3.0.CO
[2]  
2-0
[3]   Activation of the cGMP/nitric oxide signal transduction system by nicotine in the retina [J].
Blute, TA ;
Strang, C ;
Keyser, KT ;
Eldred, WD .
VISUAL NEUROSCIENCE, 2003, 20 (02) :165-176
[4]   Visual hallucinations in Lewy body disease relate to Lewy bodies in the temporal lobe [J].
Harding, AJ ;
Broe, GA ;
Halliday, GM .
BRAIN, 2002, 125 :391-403
[5]  
Marmor MF, 1999, DOC OPHTHALMOL, V97, P143
[6]   Retinal involvement in dementia with Lewy bodies: A clue to hallucinations? [J].
Maurage, CA ;
Ruchoux, MM ;
de Vos, R ;
Surguchov, A ;
Destree, A .
ANNALS OF NEUROLOGY, 2003, 54 (04) :542-547
[7]   Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study [J].
McKeith, I ;
Del Ser, T ;
Spano, P ;
Emre, M ;
Wesnes, K ;
Anand, R ;
Cicin-Sain, A ;
Ferrara, R ;
Spiegel, R .
LANCET, 2000, 356 (9247) :2031-2036
[8]   Report of the second dementia with Lewy body international workshop - Diagnosis and treatment [J].
McKeith, IG ;
Perry, EK ;
Perry, RH .
NEUROLOGY, 1999, 53 (05) :902-905
[10]   The pattern electroretinogram in Parkinson's disease reveals lack of retinal spatial tuning [J].
Tagliati, M ;
BodisWollner, I ;
Yahr, MD .
EVOKED POTENTIALS-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1996, 100 (01) :1-11