Derivatives of L-pyrimidylalanine

被引：9

作者：

Zvilichovsky, G

Gurvich, V

机构：

[1] Department of Organic Chemistry, Hebrew University of Jerusalem

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1997年 / 07期

关键词：

D O I：

10.1039/a604879j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically active derivatives of L-isoxazolo[2,3-a]pyrimidin-4-ylalanine are prepared by the combination of Birch reduction of the phenyl ring of L-phenylalanine, followed by ozonolysis and condensation with 3-amino-5-oxo-4-phenyl-2,5-dihydroisoxazole. Ring cleavage of the five-membered ring by reduction, oxidation and nucleophiles gives pyrimidylalanine derivatives.

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页码：1069 / 1071

页数：3

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