Fight or learn to live with the consequences?

被引:61
作者
Boots, Michael [1 ]
机构
[1] Univ Sheffield, Sheffield S10 2TN, S Yorkshire, England
关键词
D O I
10.1016/j.tree.2008.01.006
中图分类号
Q14 [生态学(生物生态学)];
学科分类号
071012 ; 0713 ;
摘要
Individuals can fight their infectious diseases by reducing the growth of a pathogen (resistance), but they can also ameliorate the disease it causes (tolerance). A recent paper shows that there is variation between mouse strains in tolerance to a rodent malaria and that this was negatively correlated with resistance. This is important, because tolerance has major implications for the epidemiology and coevolution of host-parasite interactions, but has been neglected in the animal literature.
引用
收藏
页码:248 / 250
页数:3
相关论文
共 15 条
[1]   The evolution of costly resistance in host-parasite systems [J].
Boots, M ;
Haraguchi, Y .
AMERICAN NATURALIST, 1999, 153 (04) :359-370
[2]   TRADEOFF BETWEEN RESISTANCE AND TOLERANCE TO HERBIVORE DAMAGE IN A MORNING GLORY [J].
FINEBLUM, WL ;
RAUSHER, MD .
NATURE, 1995, 377 (6549) :517-520
[3]   Host-parasite interactions for virulence and resistance in a malaria model system [J].
Grech, K. ;
Watt, K. ;
Read, A. F. .
JOURNAL OF EVOLUTIONARY BIOLOGY, 2006, 19 (05) :1620-1630
[4]   Genetic variation for disease resistance and tolerance among Arabidopsis thaliana accessions [J].
Kover, PX ;
Schaal, BA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (17) :11270-11274
[5]   Superspreading and the effect of individual variation on disease emergence [J].
Lloyd-Smith, JO ;
Schreiber, SJ ;
Kopp, PE ;
Getz, WM .
NATURE, 2005, 438 (7066) :355-359
[6]   Virulence in malaria: an evolutionary viewpoint [J].
Mackinnon, MJ ;
Read, AF .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2004, 359 (1446) :965-986
[7]  
Mauricio R, 1997, ECOLOGY, V78, P1301, DOI 10.1890/0012-9658(1997)078[1301:VITDSO]2.0.CO
[8]  
2
[9]  
Miller MR, 2006, EVOLUTION, V60, P945, DOI 10.1111/j.0014-3820.2006.tb01173.x
[10]   The evolution of host resistance: Tolerance and control as distinct strategies [J].
Miller, MR ;
White, A ;
Boots, M .
JOURNAL OF THEORETICAL BIOLOGY, 2005, 236 (02) :198-207