Mechanism of aromatic amino acid hydroxylation

[1] Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation [J]. JOURNAL OF MOLECULAR BIOLOGY, 2002, 320 (05) : 1095 - 1108

[2] High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin [J]. JOURNAL OF MOLECULAR BIOLOGY, 2001, 314 (02) : 279 - 291

[3] IDENTIFICATION OF METAL LIGANDS IN CU(II)-INHIBITED CHROMOBACTERIUM-VIOLACEUM PHENYLALANINE-HYDROXYLASE BY ELECTRON-SPIN ECHO ENVELOPE MODULATION ANALYSIS OF HISTIDINE TO SERINE MUTATIONS [J]. BIOCHEMISTRY, 1994, 33 (28) : 8532 - 8537

[4] Mechanism of aromatic hydroxylation by an activated feIV=O core in tetrahydrobiopterin-dependent hydroxylases [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2003, 9 (17) : 4055 - 4067

[5] Mechanism of dioxygen cleavage in tetrahydrobiopterin-dependent amino acid hydroxylases [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2003, 9 (01) : 106 - 115

[6] TAUTOMERIC NATURE OF QUINONOID 6,7-DIMETHYL-7,8-DIHYDRO-6H-PTERIN IN AQUEOUS-SOLUTION - A N-15-NMR STUDY [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (12) : 3706 - 3712

[7] BLAIR JA, 1974, J C S P2, V2, P80

[8] AN EXAMINATION OF THE COPPER REQUIREMENT OF PHENYLALANINE-HYDROXYLASE FROM CHROMOBACTERIUM-VIOLACEUM [J]. BIOCHEMISTRY, 1993, 32 (51) : 14132 - 14138

[9] MECHANISM OF METAL-INDEPENDENT HYDROXYLATION BY CHROMOBACTERIUM-VIOLACEUM PHENYLALANINE-HYDROXYLASE [J]. BIOCHEMISTRY, 1995, 34 (22) : 7525 - 7532

[10] Phenylalanine hydroxylase from Chromobacterium violaceum -: Uncoupled oxidation of tetrahydropterin and the role of iron in hyroxylation [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (40) : 25594 - 25601

[1] Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation [J]. JOURNAL OF MOLECULAR BIOLOGY, 2002, 320 (05) : 1095 - 1108

[2] High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin [J]. JOURNAL OF MOLECULAR BIOLOGY, 2001, 314 (02) : 279 - 291

[3] IDENTIFICATION OF METAL LIGANDS IN CU(II)-INHIBITED CHROMOBACTERIUM-VIOLACEUM PHENYLALANINE-HYDROXYLASE BY ELECTRON-SPIN ECHO ENVELOPE MODULATION ANALYSIS OF HISTIDINE TO SERINE MUTATIONS [J]. BIOCHEMISTRY, 1994, 33 (28) : 8532 - 8537

[4] Mechanism of aromatic hydroxylation by an activated feIV=O core in tetrahydrobiopterin-dependent hydroxylases [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2003, 9 (17) : 4055 - 4067

[5] Mechanism of dioxygen cleavage in tetrahydrobiopterin-dependent amino acid hydroxylases [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2003, 9 (01) : 106 - 115

[6] TAUTOMERIC NATURE OF QUINONOID 6,7-DIMETHYL-7,8-DIHYDRO-6H-PTERIN IN AQUEOUS-SOLUTION - A N-15-NMR STUDY [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (12) : 3706 - 3712

[7] BLAIR JA, 1974, J C S P2, V2, P80

[8] AN EXAMINATION OF THE COPPER REQUIREMENT OF PHENYLALANINE-HYDROXYLASE FROM CHROMOBACTERIUM-VIOLACEUM [J]. BIOCHEMISTRY, 1993, 32 (51) : 14132 - 14138

[9] MECHANISM OF METAL-INDEPENDENT HYDROXYLATION BY CHROMOBACTERIUM-VIOLACEUM PHENYLALANINE-HYDROXYLASE [J]. BIOCHEMISTRY, 1995, 34 (22) : 7525 - 7532

[10] Phenylalanine hydroxylase from Chromobacterium violaceum -: Uncoupled oxidation of tetrahydropterin and the role of iron in hyroxylation [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (40) : 25594 - 25601