Peculiarities of a novel bioenzymatic reactor using carbon nanotubes as enzyme activity enhancers: Application to arginase

被引:16
作者
Andre, Claire [1 ,2 ,3 ]
Agiovlasileti, Danai [1 ,2 ,3 ]
Guillaume, Yves Claude [1 ,2 ,3 ]
机构
[1] Univ Franche Comte, F-25000 Besancon, France
[2] CHU Besancon, F-25000 Besancon, France
[3] EA4267 Equipe Bio Analyt Synth EBAS, F-25000 Besancon, France
关键词
Carbon nanotube; Arginase; Enzyme; Activity enhancer; HPLC; NOR-L-ARGININE; STATIONARY-PHASE; CHROMATOGRAPHIC COLUMN; GAS-CHROMATOGRAPHY; IMMOBILIZATION; INHIBITOR; HPLC;
D O I
10.1016/j.talanta.2011.07.077
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Multiwalled carbon nanotubes have been entrapped in a porous monolithic chromatographic support. This support was used for the covalent immobilization of the arginase enzyme a novel target in hypertension. The effect of the nanotube (NT) amount into the monolith was analyzed. The obtained results demonstrated the ability of carbon nanotubes to increase significantly the performance of this novel bioactive support. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:2703 / 2706
页数:4
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