Allelic diversity of the Helicobacter pylori vacuolating cytotoxin gene in South Africa:: Rarity of the vacA s1a genotype and natural occurrence of an s2/m1 allele

被引：63

作者：

Letley, DP

Lastovica, A

Louw, JA

Hawkey, CJ

Atherton, JC

机构：

[1] Univ Nottingham, Div Gastroenterol, Nottingham NG7 2RD, England

[2] Univ Nottingham, Inst Infect & Immun, Nottingham NG7 2RD, England

[3] Univ Cape Town, ZA-7925 Cape Town, South Africa

[4] Groote Schuur Hosp, ZA-7925 Cape Town, South Africa

[5] Res Cross Childrens Hosp, Cape Town, South Africa

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1999年 / 37卷 / 04期

关键词：

D O I：

10.1128/JCM.37.4.1203-1205.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We describe the rarity of Helicobacter pylori strains of vacuolating cytotoxin type sla (the type most commonly associated with peptic ulceration in the United States) among black and mixed-race South Africans. We also provide the first description of a naturally occurring strain with the vacA allelic structure s2/m1.

引用

页码：1203 / 1205

页数：3

共 14 条

[1]

Atherton J. C., 1996, Gut, V39, pA73

[2] MOSAICISM IN VACUOLATING CYTOTOXIN ALLELES OF HELICOBACTER-PYLORI - ASSOCIATION OF SPECIFIC VACA TYPES WITH CYTOTOXIN PRODUCTION AND PEPTIC-ULCERATION [J].