Faces and phases of human CD8+ T-cell development

被引：166

作者：

Hamann, D

Roos, MTL

van Lier, RAW

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Clin Viro Immunol, NL-1105 AZ Amsterdam, Netherlands

[2] Univ Amsterdam, Acad Med Ctr, Dept Immunobiol, CLB, NL-1105 AZ Amsterdam, Netherlands

[3] Univ Amsterdam, Acad Med Ctr, Expt & Clin Immunol Lab, NL-1105 AZ Amsterdam, Netherlands

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 04期

关键词：

D O I：

10.1016/S0167-5699(99)01444-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

After viral infection, naive CD8(+) T cells become activated and either differentiate info effector cells, which eliminate virus-infected cells, or convert to memory-type T cells, awaiting re-challenge with virus. Here, Dorte Hamann and colleagues propose a model for antigen-induced differentiation of human CD8(+) T cells in vivo and discuss ifs implications for the lineage relation between memory and effector T cells.

引用

收藏

页码：177 / 180

页数：4

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