The murine Cd48 gene:: allelic polymorphism in the IgV-like region

被引：7

作者：

Cabrero, JG

Freeman, GJ

Reiser, H

机构：

[1] Hammersmith Hosp, Imperial Coll, Sch Med, Dept Immunol,Div Med, London W12 0NN, England

[2] Fdn Jimenez Diaz, Unidad Invest, E-28040 Madrid, Spain

[3] Harvard Univ, Sch Med, Dept Med, Boston, MA USA

[4] Dana Farber Canc Inst, Dept Adult Oncol, Boston, MA 02115 USA

来源：

EUROPEAN JOURNAL OF IMMUNOGENETICS | 1998年 / 25卷 / 06期

基金：

英国惠康基金;

关键词：

D O I：

10.1046/j.1365-2370.1998.00136.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The murine CD48 molecule is a member of the immunoglobulin superfamily which regulates the activation of T lymphocytes. Prior cloning experiments using mRNA from two different mouse strains had yielded discrepant sequences within the IgV-like domain of murine CD48. To resolve this issue, we have directly sequenced genomic DNA of 10 laboratory strains and two inbred strains of wild origin. The results of our analysis reveal an allelic polymorphism within the IgV-like domain of murine CD48.

引用

页码：421 / 423

页数：3

共 12 条

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