The cyclin K/Cdk12 complex An emerging new player in the maintenance of genome stability

被引：25

作者：

Blazek, Dalibor ^{[1
]}

机构：

[1] Masaryk Univ, Cent European Inst Technol CEITEC, Brno, Czech Republic

来源：

CELL CYCLE | 2012年 / 11卷 / 06期

关键词：

TRANSCRIPTION; ELONGATION;

D O I：

10.4161/cc.11.6.19678

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

引用

页码：1049 / 1050

页数：2

共 10 条

[1]

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1 [J].

Bartkowiak, Bartlomiej ;

Liu, Pengda ;

Phatnani, Hemali P. ;

Fuda, Nicholas J. ;

Cooper, Jeffrey J. ;

Price, David H. ;

Adelman, Karen ;

Lis, John T. ;

Greenleaf, Arno L. .

GENES & DEVELOPMENT, 2010, 24 (20) :2303-2316

[2]

Integrated genomic analyses of ovarian carcinoma [J].

Bell, D. ;

Berchuck, A. ;

Birrer, M. ;

Chien, J. ;

Cramer, D. W. ;

Dao, F. ;

Dhir, R. ;

DiSaia, P. ;

Gabra, H. ;

Glenn, P. ;

Godwin, A. K. ;

Gross, J. ;

Hartmann, L. ;

Huang, M. ;

Huntsman, D. G. ;

Iacocca, M. ;

Imielinski, M. ;

Kalloger, S. ;

Karlan, B. Y. ;

Levine, D. A. ;

Mills, G. B. ;

Morrison, C. ;

Mutch, D. ;

Olvera, N. ;

Orsulic, S. ;

Park, K. ;

Petrelli, N. ;

Rabeno, B. ;

Rader, J. S. ;

Sikic, B. I. ;

Smith-McCune, K. ;

Sood, A. K. ;

Bowtell, D. ;

Penny, R. ;

Testa, J. R. ;

Chang, K. ;

Dinh, H. H. ;

Drummond, J. A. ;

Fowler, G. ;

Gunaratne, P. ;

Hawes, A. C. ;

Kovar, C. L. ;

Lewis, L. R. ;

Morgan, M. B. ;

Newsham, I. F. ;

Santibanez, J. ;

Reid, J. G. ;

Trevino, L. R. ;

Wu, Y. -Q. ;

Wang, M. .

NATURE, 2011, 474 (7353) :609-615

[3]

HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer [J].

Benusiglio, P. R. ;

Pharoah, P. D. ;

Smith, P. L. ;

Lesueur, F. ;

Conroy, D. ;

Luben, R. N. ;

Dew, G. ;

Jordan, C. ;

Dunning, A. ;

Easton, D. F. ;

Ponder, B. A. J. .

BRITISH JOURNAL OF CANCER, 2006, 95 (12) :1689-1695

[4]

The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes [J].

Blazek, Dalibor ;

Kohoutek, Jiri ;

Bartholomeeusen, Koen ;

Johansen, Eric ;

Hulinkova, Petra ;

Luo, Zeping ;

Cimermancic, Peter ;

Ule, Jernej ;

Peterlin, B. Matija .

GENES & DEVELOPMENT, 2011, 25 (20) :2158-2172

[5]

Identification and characterization of the CDK12/cyclin L1 complex involved in alternative splicing regulation [J].

Chen, HH ;

Wang, YC ;

Fann, MJ .

MOLECULAR AND CELLULAR BIOLOGY, 2006, 26 (07) :2736-2745

[6]

The Set2-RPB1 Interaction Domain of Human RECQ5 Is Important for Transcription-Associated Genome Stability [J].

Li, Min ;

Xu, Xiaohua ;

Liu, Yilun .

MOLECULAR AND CELLULAR BIOLOGY, 2011, 31 (10) :2090-2099

[7]

DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation [J].

Munoz, Manuel J. ;

Perez Santangelo, M. Soledad ;

Paronetto, Maria P. ;

de la Mata, Manuel ;

Pelisch, Federico ;

Boireau, Stephanie ;

Glover-Cutter, Kira ;

Ben-Dov, Claudia ;

Blaustein, Matias ;

Lozano, Juan J. ;

Bird, Gregory ;

Bentley, David ;

Bertrand, Edouard ;

Kornblihtt, Alberto R. .

CELL, 2009, 137 (04) :708-720

[8]

Budding yeast CTDK-I is required for DNA damage-induced transcription [J].

Ostapenko, D ;

Solomon, MJ .

EUKARYOTIC CELL, 2003, 2 (02) :274-283

[9]

A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability [J].

Paulsen, Renee D. ;

Soni, Deena V. ;

Wollman, Roy ;

Hahn, Angela T. ;

Yee, Muh-Ching ;

Guan, Anna ;

Hesley, Jayne A. ;

Miller, Steven C. ;

Cromwell, Evan F. ;

Solow-Cordero, David E. ;

Meyer, Tobias ;

Cimprich, Karlene A. .

MOLECULAR CELL, 2009, 35 (02) :228-239

[10]

Genetic and Structural Variation in the Gastric Cancer Kinome Revealed through Targeted Deep Sequencing [J].

Zang, Zhi Jiang ;

Ong, Choon Kiat ;

Cutcutache, Ioana ;

Yu, Willie ;

Zhang, Shen Li ;

Huang, Dachuan ;

Ler, Lian Dee ;

Dykema, Karl ;

Gan, Anna ;

Tao, Jiong ;

Lim, Siyu ;

Liu, Yujing ;

Futreal, P. Andrew ;

Grabsch, Heike ;

Furge, Kyle A. ;

Goh, Liang Kee ;

Rozen, Steve ;

Teh, Bin Tean ;

Tan, Patrick .

CANCER RESEARCH, 2011, 71 (01) :29-39

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