The synthesis of modified D- and L-anhydrohexitol nucleosides

被引:14
作者
Andersen, MW [1 ]
Daluge, SM [1 ]
Kerremans, L [1 ]
Herdewijn, P [1 ]
机构
[1] CATHOLIC UNIV LEUVEN,REGA INST MED RES,B-3000 LOUVAIN,BELGIUM
关键词
D O I
10.1016/0040-4039(96)01895-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis and antiviral activities of novel L-isomers 9-13 and modified D-guanine analogs 1d,e of recently reported anhydrohexitol nucleosides 1 are described. An efficient approach to known anhydrohexitol nucleoside precursor 2 from diacetone-D-glucose 3 is also reported. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:8147 / 8150
页数:4
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