Clinical review: The ABC of weaning failure - a structured approach

被引：158

作者：

Heunks, Leo M. ^{[1
]}

van der Hoeven, Johannes G. ^{[1
]}

机构：

[1] Radboud Univ Nijmegen, Med Ctr, Dept Intens Care Med 632, NL-6500 HB Nijmegen, Netherlands

来源：

CRITICAL CARE | 2010年 / 14卷 / 06期

关键词：

OBSTRUCTIVE PULMONARY-DISEASE; MECHANICALLY VENTILATED PATIENTS; CRITICALLY-ILL PATIENTS; INTENSIVE-CARE-UNIT; RANDOMIZED-TRIAL; CRITICAL ILLNESS; SLEEP QUALITY; DIAPHRAGM; DELIRIUM; HYPOTHYROIDISM;

D O I：

10.1186/cc9296

中图分类号：

R4 [临床医学];

学科分类号：

100218 [急诊医学];

摘要：

About 20% to 30% of patients are difficult to wean from invasive mechanical ventilation. The pathophysiology of difficult weaning is complex. Accordingly, determining the reason for difficult weaning and subsequently developing a treatment strategy require a dedicated clinician with in-depth knowledge of the pathophysiology of weaning failure. This review presents a structural framework ('ABCDE') for the assessment and treatment of difficult-to-wean patients. Earlier recognition of the underlying causes may expedite weaning from mechanical ventilation.

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