Melatonin in humans: It's about time

被引：20

作者：

Arendt, J ^{[1
]}

机构：

[1] Univ Surrey, Ctr Chronobiol, Guildford GU2 5XH, Surrey, England

来源：

JOURNAL OF NEUROENDOCRINOLOGY | 2005年 / 17卷 / 08期

关键词：

D O I：

10.1111/j.1365-2826.2005.01333.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Melatonin signals night time by its rhythmic profile of secretion. Its measurement provides the best indicator of internal circadian clock timing. Treatment with melatonin induces sleepiness and lowers body temperature during 'biological day' (i.e. when its endogenous secretion is minimal) and it acts as a 'chronobiotic' to change the timing of the circadian clock. It has been used successfully to treat disorders of biological rhythms in humans.

引用

页码：537 / 538

页数：2