Achilles' heel of cancer?

被引：50

作者：

Vogelstein, B ^{[1
]}

Kinzler, KW

机构：

[1] Johns Hopkins Univ, Sch Med, Howard Hughes Med Inst, Baltimore, MD 21231 USA

[2] Johns Hopkins Univ, Sch Med, Johns Hopkins Oncol Ctr, Baltimore, MD 21231 USA

来源：

NATURE | 2001年 / 412卷 / 6850期

关键词：

D O I：

10.1038/35091170

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The p53 protein is inactivated in most human cancers. One outcome is a defect in controlling cell division. Might a virus that exploits this defect prove useful in treating cancer?

引用

页码：865 / 866

页数：2

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