Effects of hair dyeing on DNA damage in human lymphocytes

被引：17

作者：

Cho, JA

Oh, E

Lee, E

Sul, D

机构：

[1] Korea Univ, Dept Prevent Med, Coll Med, Seoul 136701, South Korea

[2] Seokyeong Univ, Dept Beauty Arts, Seoul, South Korea

[3] Korea Univ, Grad Studies Publ Hlth, Grad Sch, Seoul 136701, South Korea

[4] Korea Univ, Inst Environm Hlth, Med Sci Res Ctr, Seoul 136701, South Korea

来源：

JOURNAL OF OCCUPATIONAL HEALTH | 2003年 / 45卷 / 06期

关键词：

comet assay; lymphocytes; hair; dye;

D O I：

10.1539/joh.45.376

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Effects of Hair Dyeing on DNA Damage in Human Lymphocytes: Jin-A CHOA, et al. Department of Beauty Arts, Seokyeong University, Korea-Comet assays were carried out to evaluate DNA damage in human lymphocytes from 20 volunteers before and after hair dyeing. DNA damage in lymphocytes was found to be slightly higher in volunteers after hair dyeing. Tail moments before and after hair dyeing were 1.47 +/- 0.41 and 1.75 +/- 0.29 respectively (p < 0.0008). DNA damage in lymphocytes showed significant difference with treatment and heating time. The tail moments after 15 min of treatment time before and after hair dyeing were 1.44 +/- 0.22 and 1.85 +/- 0.36, respectively (p = 0.0004) and the corresponding tail moments in 20 min of heating time before and after were 1.37 +/- 0.15 and 1.78 +/- 0.34 (p = 0.0002). In conclusion, we found that an acute exposure of hair dyes with heating caused DNA damages in peripheral lymphocytes and that this damage had significant association with treatment and heating time.

引用

页码：376 / 381

页数：6

共 21 条

[1]

CHEN F, 1988, CANC LETT, V126, P67

[2] Mutagenicity and toxicity studies of p-phenylenediamine and its derivatives [J].