The Mindful Brain and Emotion Regulation in Mood Disorders

被引:225
作者
Farb, Norman A. S. [1 ]
Anderson, Adam K. [1 ,2 ]
Segal, Zindel V. [1 ,3 ,4 ]
机构
[1] Baycrest Ctr Geriatr Care, Rotman Res Inst, Toronto, ON M6A 2E1, Canada
[2] Univ Toronto, Dept Psychol, Toronto, ON M5S 1A1, Canada
[3] Univ Toronto, Dept Psychiat, Cameron Wilson Chair Depress Studies, Toronto, ON, Canada
[4] Cognit Behav Therapy Clin, Mood & Anxiety Disorders Program, Dept Clin Res Ctr Addict & Mental Hlth, Toronto, ON, Canada
来源
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE | 2012年 / 57卷 / 02期
基金
加拿大健康研究院;
关键词
attention; emotion regulation; intervention; mindfulness-based cognitive therapy; mindfulness-based stress reduction; mechanism; meditation; mindfulness; neuroscience; stress; DISPOSITIONAL MINDFULNESS; PREFRONTAL CORTEX; SELF-COMPASSION; NEURAL SYSTEMS; RESTING-STATE; MEDITATION; DEPRESSION; ANXIETY; PAIN; CONNECTIVITY;
D O I
10.1177/070674371205700203
中图分类号
R749 [精神病学];
学科分类号
100204 [神经病学];
摘要
Mindfulness involves nonjudgmental attention to present-moment experience. In its therapeutic forms, mindfulness interventions promote increased tolerance of negative affect and improved well-being. However, the neural mechanisms underlying mindful mood regulation are poorly understood. Mindfulness training appears to enhance focused attention, supported by the anterior cingulate cortex and the lateral prefrontal cortex (PFC). In emotion regulation, these PFC changes promote the stable recruitment of a nonconceptual sensory pathway, an alternative to conventional attempts to cognitively reappraise negative emotion. In neural terms, the transition to nonconceptual awareness involves reducing evaluative processing, supported by midline structures of the PFC. Instead, attentional resources are directed toward a limbic pathway for present-moment sensory awareness, involving the thalamus, insula, and primary sensory regions. In patients with affective disorders, mindfulness training provides an alternative to cognitive efforts to control negative emotion, instead directing attention toward the transitory nature of momentary experience. Limiting cognitive elaboration in favour of momentary awareness appears to reduce automatic negative self-evaluation, increase tolerance for negative affect and pain, and help to engender self-compassion and empathy in people with chronic dysphoria.
引用
收藏
页码:70 / 77
页数:8
相关论文
共 71 条
[1]
Inhibition and the right inferior frontal cortex [J].
Aron, AR ;
Robbins, TW ;
Poldrack, RA .
TRENDS IN COGNITIVE SCIENCES, 2004, 8 (04) :170-177
[3]
An investigation of brain processes supporting meditation [J].
Baerentsen, Klaus B. ;
Stodkilde-Jorgensen, Hans ;
Sommerlund, Bo ;
Hartmann, Tue ;
Damsgaard-Madsen, Johannes ;
Fosnaes, Mark ;
Green, Anders C. .
COGNITIVE PROCESSING, 2010, 11 (01) :57-84
[4]
Neural correlates of attentional expertise in long-term meditation practitioners [J].
Brefczynski-Lewis, J. A. ;
Lutz, A. ;
Schaefer, H. S. ;
Levinson, D. B. ;
Davidson, R. J. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (27) :11483-11488
[5]
Neural mechanisms of empathy in humans: A relay from neural systems for imitation to limbic areas [J].
Carr, L ;
Iacoboni, M ;
Dubeau, MC ;
Mazziotta, JC ;
Lenzi, GL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (09) :5497-5502
[6]
Executive "brake failure" following deactivation of human frontal lobe [J].
Chambers, CD ;
Bellgrove, MA ;
Stokes, MG ;
Henderson, TR ;
Garavan, H ;
Robertson, IH ;
Morris, AP ;
Mattingley, JB .
JOURNAL OF COGNITIVE NEUROSCIENCE, 2006, 18 (03) :444-455
[7]
TEMPERAMENT, PERSONALITY, AND THE MOOD AND ANXIETY DISORDERS [J].
CLARK, LA ;
WATSON, D ;
MINEKA, S .
JOURNAL OF ABNORMAL PSYCHOLOGY, 1994, 103 (01) :103-116
[8]
Neural correlates of rumination in depression [J].
Cooney, Rebecca E. ;
Joormann, Jutta ;
Eugene, Fanny ;
Dennis, Emily L. ;
Gotlib, Ian H. .
COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE, 2010, 10 (04) :470-478
[10]
Neural correlates of dispositional mindfulness during affect labeling [J].
Creswell, J. David ;
Way, Baldwin M. ;
Eisenberger, Naomi I. ;
Lieberman, Matthew D. .
PSYCHOSOMATIC MEDICINE, 2007, 69 (06) :560-565