Chemokine receptors and HIV-1: the fusion of two major research fields

被引：68

作者：

Horuk, R ^{[1
]}

机构：

[1] Berlex Biosci, Dept Immunol, Richmond, CA 94804 USA

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 02期

关键词：

D O I：

10.1016/S0167-5699(98)01396-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Chemokines mediate their effects by binding to cell-surface receptors that belong ro the seven-transmembrane-domain superfamily of proteins. Chemokine receptors have been subject to intense scrutiny following the recent discovery that several of them are co-receptors for HIV-1. Here, Richard Horuk reviews the latest developments in chemokine receptor research with a particular focus on their role as HIV-1 co-receptors.

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页码：89 / 94

页数：6

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